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After graduating from high school, Debra entered New York University, where she studied theater and acting. Her talent was noticed while still studying, and she quickly caught the attention of directors.

Debra Messing has appeared in numerous films and television series, including:

- "Finding a Husband" (1997): In this romantic comedy, she played a major role, creating a unique image of a young and sincere woman striving to find true love.

- "Rich Man and the Poor Man" (1999-2006): In this popular television series, she reprised the role of Grace Adler, an attractive and fun heroine whose life is full of adventure and unexpected twists.

- "Charms of the Charmer" (2012-2020): In this comedy series, she co-starred, bringing many funny and bright moments to the audience.

Debra Messing continues to delight audiences with her talent and energy. Her vivid and sensual performances make her one of the most sought-after actresses in Hollywood, and her influence on film and television remains significant.